Description

(Rs)-2-(2-Hydroxy-3-Isopropylaminopropoxy)-4,6-Dimethylbenzophenone Hydrochloride is a high-purity, non-racemic chiral compound primarily utilized as a critical pharmaceutical intermediate. Its value lies in its role as a key building block for the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in cardiovascular and β-blocker research. This product is essential for manufacturers and R&D laboratories in the pharmaceutical and fine chemical sectors seeking a reliable, high-quality chiral synthon for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of β-adrenergic blocking agents (β-blockers).
• API Development: Used in research and development for novel cardiovascular and other therapeutic active pharmaceutical ingredients.
• Asymmetric Synthesis: Serves as a valuable chiral building block in stereoselective organic synthesis.
• Chemical Research: Employed in academic and industrial laboratories for pharmacological studies and structure-activity relationship (SAR) investigations.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	(Rs)-2-(2-Hydroxy-3-Isopropylaminopropoxy)-4,6-Dimethylbenzophenone Hydrochloride
CAS No.	62261-89-6
Molecular Formula	C21H28ClNO3
Molecular Weight	377.90 g/mol
Synonyms	2-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-4,6-dimethylbenzophenone Hydrochloride; (RS)-2-[2-Hydroxy-3-(isopropylamino)propoxy]-4,6-dimethylbenzophenone Hydrochloride; Benzophenone, 2-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-4,6-dimethyl-, hydrochloride; (R,S)-Carvedilol Impurity; Carvedilol Related Compound; Carvedilol Intermediate; 62261-89-6 (CAS)
EINECS	Contact for details

Quality Control

Our (Rs)-2-(2-Hydroxy-3-Isopropylaminopropoxy)-4,6-Dimethylbenzophenone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets exacting standards for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) with full traceability is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (Rs isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.