Description

4-(2,2,2-Trifluoroethoxy)Nitrobenzene is a specialized fluorinated aromatic nitro compound, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoroethoxy substituent, imparts distinct electronic and steric properties that are valuable for modifying molecular characteristics. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients. Its reliable synthesis and consistent quality are paramount for accelerating innovation in these high-value industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoroethoxy group can improve lipophilicity and biological activity.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in advanced display technologies.
• Organic Electronic Materials: Intermediate for synthesizing electron-deficient aromatic units used in organic semiconductors and OLED materials.
• Complex Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Custom Fluorination Chemistry: A valuable starting material for introducing the 2,2,2-trifluoroethoxy functional group into more complex molecular architectures.

Basic Information

Product Name	4-(2,2,2-Trifluoroethoxy)Nitrobenzene
CAS No.	62149-35-3
Molecular Formula	C8H6F3NO3
Molecular Weight	221.14 g/mol
Synonyms	1-Nitro-4-(2,2,2-trifluoroethoxy)benzene; p-(2,2,2-Trifluoroethoxy)nitrobenzene; 4-Nitrophenyl 2,2,2-trifluoroethyl ether; 2,2,2-Trifluoroethyl 4-nitrophenyl ether; Benzene, 1-nitro-4-(2,2,2-trifluoroethoxy)-; Nitrobenzene, 4-(2,2,2-trifluoroethoxy)-
EINECS	Contact for details

Quality Control

Every batch of 4-(2,2,2-Trifluoroethoxy)Nitrobenzene is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency meet the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.