Description

4,6-Difluoroserotonin is a fluorinated derivative of the key neurotransmitter serotonin, offering enhanced metabolic stability and altered receptor binding affinity. This compound is a critical research-grade biochemical used extensively in neuroscience and pharmacology to study serotonin receptor subtypes and signaling pathways. It serves as a valuable building block and reference standard for pharmaceutical R&D, particularly in the development of novel CNS-active agents and neurochemical probes.

Application

• Neuroscience Research: As a potent tool compound for studying 5-HT (serotonin) receptor pharmacology, function, and distribution.
• Pharmaceutical Development: A key intermediate in the synthesis of novel fluorinated drug candidates targeting neurological and psychiatric disorders.
• Biochemical Assays: Used as a reference standard in high-throughput screening (HTS) and competitive binding assays to evaluate new therapeutic compounds.
• Metabolic Studies: Employed to investigate the structure-activity relationships (SAR) and metabolic pathways of fluorinated neurotransmitters.
• Academic Research: Fundamental studies in chemical biology and medicinal chemistry to understand the impact of fluorination on bioactivity.

Basic Information

Product Name	4,6-Difluoroserotonin
CAS No.	62105-98-0
Molecular Formula	C₁₀H₁₀F₂N₂O
Molecular Weight	212.20 g/mol
Synonyms	4,6-Difluoro-5-hydroxytryptamine; 2-(5,7-Difluoro-1H-indol-3-yl)ethan-1-amine; 5,7-Difluoroserotonin; 5-Hydroxy-5,7-difluorotryptamine; 4,6-Difluoro-5-HT; 4,6-DF-5-HT
EINECS	Contact for details

Quality Control

We supply 4,6-Difluoroserotonin as a high-purity research chemical. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with research-grade standards. Comprehensive analytical data, including HPLC purity and spectroscopic confirmation (NMR, MS), is documented. Certificates of Analysis (COA) are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.