Description

R-Bupranolol is a high-purity, single-enantiomer pharmaceutical intermediate and reference standard. This compound is a key chiral building block in the research and development of β-adrenergic receptor antagonists. It is essential for pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and analytical method development. Our supply ensures consistent quality and reliable availability for critical R&D and production needs.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of enantiomerically pure β-blocker APIs.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) testing in pharmaceutical laboratories.
• Biochemical Research: Employed in pharmacological studies to investigate β-adrenergic receptor binding and activity.
• Process Development: Serves as a key material for optimizing and scaling up synthetic routes in process chemistry.
• Impurity Standard: Utilized as a certified reference material to identify and quantify related substances in final drug products.

Basic Information

Product Name	R-Bupranolol
CAS No.	61877-83-6
Molecular Formula	C14H22NO2Cl
Molecular Weight	271.79 g/mol
Synonyms	(R)-Bupranolol; (R)-1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)propan-2-ol; (R)-1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol; R(-)-Bupranolol; Dextro-Bupranolol; (2R)-1-(tert-Butylamino)-3-[(2-chloro-5-methyl)phenoxy]propan-2-ol; UNII-6V9V2RYJ6R; (R)-(-)-Bupranolol
EINECS	Contact for details

Quality Control

Our R-Bupranolol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and enantiomeric excess. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% (R-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.