Description

Clemastine CAS NO 61826-28-6 is a potent, selective histamine H1-receptor antagonist belonging to the ethanolamine class of antihistamines. This compound is a critical active pharmaceutical ingredient (API) valued for its efficacy in managing allergic conditions. It is primarily required by pharmaceutical manufacturers and research institutions for the development and production of anti-allergy medications. Our supply ensures high purity and batch-to-batch consistency for reliable formulation.

Application

• Primary Active Pharmaceutical Ingredient (API) in anti-allergy tablet and syrup formulations.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Key intermediate in advanced pharmaceutical research for novel antihistamine derivatives.
• Raw material for compounding pharmacies specializing in custom allergy treatments.
• Biochemical tool for pharmacological studies targeting histamine H1-receptors.
• Starting material for the synthesis of deuterated or other labeled clemastine compounds for clinical research.

Basic Information

Product Name	Clemastine
CAS No.	61826-28-6
Molecular Formula	C21H26ClNO
Molecular Weight	343.89 g/mol
Synonyms	Meclastin; Mecloprodin; Tavegil; Tavegyl; Tavist; Clemastine Fumarate (salt form); (+)-(2R)-2-[2-[(R)-1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine; 1-Methyl-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]pyrrolidine
EINECS	Contact for details

Quality Control

Our Clemastine is manufactured and tested under strict quality management systems. Each batch undergoes comprehensive analysis to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with in-house specifications. We support compliance with major pharmacopoeial standards, and custom purity grades are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect the hygroscopic material from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.