Description

(6α,9β,11β,16α)-9,11-Epoxy-6-Fluoro-21-Hydroxy-16-Methyl-Pregna-1,4-Diene-3,20-Dione is a high-purity synthetic steroid derivative, valued for its role as a critical pharmaceutical intermediate. Its complex molecular structure, featuring a 9,11-epoxy bridge and a fluorine substituent, makes it a key building block in the synthesis of advanced corticosteroid and anti-inflammatory agents. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical suppliers focused on producing next-generation therapeutic steroids.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent topical and systemic corticosteroids.
• Active Pharmaceutical Ingredient (API) Development: Used in R&D for creating novel steroid-based drugs with enhanced efficacy and reduced side effects.
• Biochemical Research: Serves as a reference standard and a tool for studying steroid receptor interactions and metabolic pathways.
• Process Chemistry: Employed in scale-up and optimization of steroid manufacturing processes within GMP environments.
• Fine Chemical Synthesis: Utilized for the custom synthesis of specialized steroid analogs for clinical and preclinical studies.

Basic Information

Product Name	(6α,9β,11β,16α)-9,11-Epoxy-6-Fluoro-21-Hydroxy-16-Methyl-Pregna-1,4-Diene-3,20-Dione
CAS No.	61618-89-1
Molecular Formula	C22H27FO5
Molecular Weight	390.45 g/mol
Synonyms	9,11β-Epoxy-6α-fluoro-16α-methyl-21-hydroxypregna-1,4-diene-3,20-dione; 6α-Fluoro-9β,11β-epoxy-16α-methyl-21-hydroxypregna-1,4-diene-3,20-dione; 6α-Fluoro-9β,11β-epoxy-16α-methylprednisolone; 6α-Fluoro-9β,11β-epoxy-16α-methyl-1,4-pregnadiene-11β,21-diol-3,20-dione; Fludroxycortide Impurity; Flurandrenolone related compound; 61618-89-1
EINECS	Contact for details

Quality Control

Our (6α,9β,11β,16α)-9,11-Epoxy-6-Fluoro-21-Hydroxy-16-Methyl-Pregna-1,4-Diene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for pharmaceutical R&D and intermediate use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.