Description

Cortisol-21-Palmitate is a lipophilic ester derivative of the endogenous glucocorticoid hormone cortisol. This chemical modification enhances its lipid solubility, making it a valuable intermediate for research and development in advanced drug delivery systems and prodrug strategies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of specialty biochemicals. The compound is offered under stringent quality control to ensure reliability for sensitive applications.

Application

• Pharmaceutical Research & Development: Key intermediate in the synthesis of novel corticosteroid prodrugs designed for enhanced topical or transdermal delivery.
• Biochemical Reference Standard: Used as a high-purity analytical standard in method development and validation for steroid analysis via HPLC, LC-MS, or GC-MS.
• Prodrug Formulation Studies: Investigated for its potential to improve the pharmacokinetic profile, bioavailability, and targeted release of cortisol.
• Metabolic Pathway Research: Serves as a tool compound in studies exploring steroid metabolism, esterification, and hydrolysis mechanisms.
• Specialty Chemical Synthesis: A building block for the custom synthesis of other steroidal esters with tailored properties for specific industrial or research applications.

Basic Information

Product Name	Cortisol-21-Palmitate
CAS No.	61366-96-9
Molecular Formula	C37H60O6
Molecular Weight	600.87 g/mol
Synonyms	Hydrocortisone 21-Palmitate; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 21-palmitate; Cortisol Palmitate; Hydrocortisone Palmitate; 21-Palmitoyloxycortisol; Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, 21-(1-oxohexadecyl)oxy)-, (11β)-; Cortisol Hexadecanoate
EINECS	Contact for details

Quality Control

Our Cortisol-21-Palmitate is manufactured and tested to meet high-purity standards suitable for research and development. Each batch undergoes rigorous analytical characterization to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing results from HPLC, NMR, and other relevant spectroscopic methods. We adhere to a cGMP-compliant quality management system to guarantee traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.