Description

20,21-Dihydroxy-16Alpha-Methylpregna-1,4,9(11),17(20)-Tetraen-3-One 20,21-Di(Acetate) is a high-purity steroid derivative of significant interest in advanced pharmaceutical synthesis. This compound serves as a critical synthetic intermediate, valued for its specific molecular framework that enables the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of steroidal drugs, particularly for exploring new anti-inflammatory or hormonal therapies. Our supply ensures consistent quality and reliable availability for your most demanding R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Process Chemistry: Serves as a defined starting material or intermediate in optimizing scalable GMP manufacturing routes.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Used in studies investigating steroid hormone receptors and related metabolic pathways.

Basic Information

Item	Detail
Product Name	20,21-Dihydroxy-16Alpha-Methylpregna-1,4,9(11),17(20)-Tetraen-3-One 20,21-Di(Acetate)
CAS No.	61339-39-7
Molecular Formula	C₂₆H₃₂O₆
Molecular Weight	440.53 g/mol
Synonyms	16α-Methylpregna-1,4,9(11),17(20)-tetraene-3,20,21-trione 20,21-diacetate; 16α-Methyl-20,21-dihydroxypregna-1,4,9(11),17(20)-tetraen-3-one 20,21-diacetate; 20,21-Diacetoxy-16α-methylpregna-1,4,9(11),17(20)-tetraen-3-one; 16α-Methyl-3-oxopregna-1,4,9(11),17(20)-tetraene-20,21-diyl diacetate
EINECS	Contact for details

Quality Control

Every batch of our 20,21-Dihydroxy-16Alpha-Methylpregna-1,4,9(11),17(20)-Tetraen-3-One 20,21-Di(Acetate) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support its use in regulated environments, with specifications typically meeting or exceeding >98.0% purity (HPLC). A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.