Description

2-Fluoro-3-Nitrobenzotrifluoride is a versatile fluorinated aromatic building block, distinguished by its trifluoromethyl and nitro substituents which confer unique electronic and steric properties. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its structure enables precise modulation of biological activity and physicochemical characteristics. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes.
• Functional Dye & Pigment Production: Employed in the synthesis of specialized dyes and pigments with improved lightfastness and color properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Organic Synthesis & Research: A valuable reagent in academic and industrial research labs for exploring new fluorination methodologies and constructing complex organic architectures.

Basic Information

Product Name	2-Fluoro-3-Nitrobenzotrifluoride
CAS No.	61324-97-8
Molecular Formula	C7H3F4NO2
Molecular Weight	209.10 g/mol
Synonyms	1-Fluoro-2-nitro-5-(trifluoromethyl)benzene; 2-Fluoro-3-nitro-α,α,α-trifluorotoluene; 3-Nitro-2-fluorobenzotrifluoride; Benzene, 1-fluoro-2-nitro-5-(trifluoromethyl)-; 2-Fluoro-α,α,α-trifluoro-3-nitrotoluene; 5-Trifluoromethyl-2-fluoro-1-nitrobenzene; 2-Fluoro-3-nitrobenzylidene trifluoride
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-Nitrobenzotrifluoride is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing full transparency on purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.