Description

Luteinizing Hormone-Releasing Factor (Pig), 6-[3-[(1,1-Dimethylethyl)Thio]-D-Valine]-9-(n-Ethyl-L-Prolinamide)-10-Deglycinamide- is a synthetic peptide analog of the native gonadotropin-releasing hormone (GnRH). This compound is engineered for enhanced stability and specific biological activity, making it a critical tool for advanced endocrinology research and pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies focused on reproductive biology, hormone regulation, and peptide-based therapeutic discovery.

Application

• Biomedical Research: Fundamental studies on the hypothalamic-pituitary-gonadal axis, receptor binding assays, and signal transduction mechanisms.
• Pharmaceutical R&D: Serving as a reference standard or active pharmaceutical ingredient (API) in the development of novel GnRH analogs for therapeutic applications.
• Veterinary Science: Research into reproductive management and fertility control in animal models, leveraging its porcine origin.
• Diagnostic Development: Use in the calibration and validation of immunoassays designed to measure GnRH or related hormone levels.
• Peptide Chemistry Studies: As a model compound for investigating structure-activity relationships (SAR) and the impact of specific amino acid modifications on peptide stability and function.

Basic Information

Product Name	Luteinizing Hormone-Releasing Factor (Pig), 6-[3-[(1,1-Dimethylethyl)Thio]-D-Valine]-9-(n-Ethyl-L-Prolinamide)-10-Deglycinamide-
CAS No.	61012-20-2
Molecular Formula	C58H86N16O12S
Molecular Weight	1191.5 g/mol
Synonyms	GnRH (Pig) Analog; [Des-Gly10, D-Val6(tBu-S), Pro9-NHEt]-LHRH; Luteinizing Hormone-Releasing Hormone (6-10) analog; LHRH (6-10) fragment analog; Gonadorelin (6-10) analog; 61012-20-2; LHRF (Pig) derivative
EINECS	Contact for details

Quality Control

Our high-purity peptide products are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry (MS) for identity confirmation, to ensure compliance with research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the assay, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep the container in a dry environment. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.