Description

2-Bromo-6Beta-Fluoro-17,21-Dihydroxy-16Beta-Methylpregna-1,4,9(11)-Triene-3,20-Dione 21-Acetate is a high-purity, advanced steroid intermediate of significant interest in pharmaceutical research and development. This compound matters as a key synthetic precursor for the production of potent glucocorticoid receptor modulators and other specialized therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on novel anti-inflammatory and immunosuppressive drugs.

Application

• Pharmaceutical Intermediate: Critical building block in the multi-step synthesis of novel glucocorticoid and corticosteroid APIs (Active Pharmaceutical Ingredients).
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and the development of new steroidal drugs.
• Process Chemistry: Serves as a key intermediate in scaling up and optimizing manufacturing routes for complex steroid-based therapeutics.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Research: Utilized in studies investigating steroid hormone receptor binding and modulation.

Basic Information

Product Name	2-Bromo-6Beta-Fluoro-17,21-Dihydroxy-16Beta-Methylpregna-1,4,9(11)-Triene-3,20-Dione 21-Acetate
CAS No.	60864-76-8
Molecular Formula	C₂₄H₂₈BrFO₆
Molecular Weight	511.39 g/mol
Synonyms	9α-Fluoro-11β,17α,21-Trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-acetate 2-bromo derivative; 2-Bromo-6β-fluoro-17,21-dihydroxy-16β-methylpregna-1,4,9(11)-triene-3,20-dione 21-acetate; 2-Bromo-6β-fluoro-16β-methylprednisolone 21-acetate; 2-Bromotriamcinolone 21-acetate; 2-Bromo-9α-fluoro-16β-methylprednisolone 21-acetate; 2-Bromo-6β-fluoro-16β-methyl-1,4,9(11)-pregnatriene-17α,21-diol-3,20-dione 21-acetate
EINECS	Contact for details

Quality Control

Our 2-Bromo-6Beta-Fluoro-17,21-Dihydroxy-16Beta-Methylpregna-1,4,9(11)-Triene-3,20-Dione 21-Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.