Description

2-Bromo-6Beta-Fluoro-11Alpha,17,21-Trihydroxy-16Beta-Methylpregna-1,4-Diene-3,20-Dione 21-Acetate is a high-purity, synthetic steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for synthesizing novel corticosteroid analogs with targeted biological activity. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new anti-inflammatory and immunosuppressive agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel halogenated corticosteroid drugs.
• Research & Development: Used in medicinal chemistry programs to study structure-activity relationships (SAR) of steroid hormones.
• Reference Standard: Serves as an analytical standard in quality control laboratories for method development and impurity profiling.
• Process Chemistry: Employed in scale-up and optimization studies for the production of active pharmaceutical ingredients (APIs).
• Biochemical Research: Investigated for its interaction with glucocorticoid and mineralocorticoid receptors in preclinical studies.

Basic Information

Item	Details
Product Name	2-Bromo-6Beta-Fluoro-11Alpha,17,21-Trihydroxy-16Beta-Methylpregna-1,4-Diene-3,20-Dione 21-Acetate
CAS No.	60864-74-6
Molecular Formula	C₂₄H₃₀BrFO₆
Molecular Weight	513.40 g/mol
Synonyms	2-Bromo-6β-Fluoro-11α,17,21-Trihydroxy-16β-Methylpregna-1,4-Diene-3,20-Dione 21-Acetate; 2-Bromo-6β-fluoro-11α,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-acetate; 2-Bromo-6-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 21-acetate; 21-Acetoxy-2-bromo-6β-fluoro-11α,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione; Halogenated Corticosteroid Intermediate; Bromofluoro Prednisolone Acetate Derivative
EINECS	Contact for details

Quality Control

Our 2-Bromo-6Beta-Fluoro-11Alpha,17,21-Trihydroxy-16Beta-Methylpregna-1,4-Diene-3,20-Dione 21-Acetate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.