Description

9Beta,11Alpha-Epoxy-6Beta-Fluoro-17,21-Dihydroxy-16Alpha-Methylpregna-1,4-Diene-3,20-Dione 17,21-Di(Acetate) is a high-purity synthetic steroid derivative, serving as a critical advanced intermediate in pharmaceutical synthesis. Its precise molecular architecture is essential for the development of potent corticosteroid-based therapeutics. This compound is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel anti-inflammatory and immunosuppressive agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent topical and systemic corticosteroids.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for new steroid-based drug candidates.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating steroid receptor interactions and metabolic pathways.
• Process Chemistry: Utilized for scaling up and optimizing manufacturing routes for final steroid APIs.

Basic Information

Product Name	9Beta,11Alpha-Epoxy-6Beta-Fluoro-17,21-Dihydroxy-16Alpha-Methylpregna-1,4-Diene-3,20-Dione 17,21-Di(Acetate)
CAS No.	60864-53-1
Molecular Formula	C₂₈H₃₅FO₇
Molecular Weight	502.58 g/mol
Synonyms	9β,11β-Epoxy-6α-fluoro-16α-methylprednisolone 17,21-diacetate; 6α-Fluoro-9β,11β-epoxy-16α-methylprednisolone 17,21-diacetate; Fluocortolone 17,21-Diacetate Impurity; 9β,11β-Epoxy-6α-fluoro-16α-methyl-1,4-pregnadiene-3,20-dione-11β,17α,21-triol 17,21-diacetate; 16α-Methyl-9β,11β-epoxy-6α-fluoroprednisolone 17,21-diacetate
EINECS	Contact for details

Quality Control

Our 9Beta,11Alpha-Epoxy-6Beta-Fluoro-17,21-Dihydroxy-16Alpha-Methylpregna-1,4-Diene-3,20-Dione 17,21-Di(Acetate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets exacting pharmaceutical intermediate standards. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.