Description

9,11Beta-Dichloro-6Beta-Fluoro-17,21-Dihydroxypregna-1,4-Diene-3,20-Dione 17,21-Di(Acetate) CAS NO 60864-41-7 is a high-purity synthetic steroid derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its complex halogenated and acetylated structure makes it a valuable precursor for the synthesis of potent glucocorticoid receptor modulators and other specialized therapeutic agents. This compound is essential for pharmaceutical chemists and R&D laboratories focused on developing novel anti-inflammatory, dermatological, and oncological treatments.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel glucocorticoid and corticosteroid APIs (Active Pharmaceutical Ingredients).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new steroid-based therapeutics.
• Preclinical Studies: Serves as a reference standard or starting material in the investigation of metabolic pathways and biological activity of halogenated steroids.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for complex steroid molecules within GMP environments.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis projects and steroid chemistry studies.

Basic Information

Product Name	9,11Beta-Dichloro-6Beta-Fluoro-17,21-Dihydroxypregna-1,4-Diene-3,20-Dione 17,21-Di(Acetate)
CAS No.	60864-41-7
Molecular Formula	C₂₅H₂₈Cl₂FO₇
Molecular Weight	545.39 g/mol
Synonyms	9β,11β-Dichloro-6β-fluoro-17α,21-dihydroxypregna-1,4-diene-3,20-dione 17,21-diacetate; 6β-Fluoro-9β,11β-dichloroprednisolone 17,21-diacetate; 9,11β-Dichloro-6β-fluoroprednisolone 17,21-diacetate; Fluocinolone Acetonide Related Compound; Halogenated Prednisolone Diacetate Derivative; 1,4-Pregnadiene-3,20-dione, 9,11-dichloro-6-fluoro-17,21-dihydroxy-, diacetate, (6β,9β,11β)-; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 9,11Beta-Dichloro-6Beta-Fluoro-17,21-Dihydroxypregna-1,4-Diene-3,20-Dione 17,21-Di(Acetate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for research and pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.