Description

Oxatomide is a potent and selective histamine H1-receptor antagonist with significant anti-allergic properties. This compound is valued for its ability to stabilize mast cells and inhibit the release of inflammatory mediators, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily utilized by research institutions and pharmaceutical manufacturers developing next-generation treatments for allergic conditions such as asthma, rhinitis, and dermatitis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced antihistamine and anti-allergic drug formulations.
• Research & Development: Used in biochemical and pharmacological research to study mast cell stabilization and histamine receptor antagonism.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the controlled production of finished dosage forms for allergy and asthma medications.
• Veterinary Medicine: Applied in the development of anti-allergic treatments for companion and livestock animals.

Basic Information

Product Name	Oxatomide
CAS No.	60607-34-3
Molecular Formula	C27H30N4O4
Molecular Weight	474.55 g/mol
Synonyms	1-[3-[4-(Diphenylmethoxy)piperidino]propyl]-2-benzimidazolinone; Oxatimide; KW-4354; Tinset; 1-(3-(4-(Diphenylmethoxy)-1-piperidinyl)propyl)-1,3-dihydro-2H-benzimidazol-2-one; 1-[3-[4-(Diphenylmethoxy)-1-piperidinyl]propyl]-1,3-dihydro-2H-benzimidazol-2-one; Oxatomidum
EINECS	262-290-5

Quality Control

Our Oxatomide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and identification by IR and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with in-house specifications and supporting cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.