Description

Methylprednisolonesuleptanate is a synthetic corticosteroid ester prodrug, primarily used in advanced pharmaceutical formulations. Its value lies in providing a controlled-release mechanism for the active glucocorticoid, methylprednisolone, enhancing therapeutic efficacy and patient compliance. This compound is essential for manufacturers in the pharmaceutical and research and development sectors, particularly for developing long-acting injectable or implantable drug delivery systems.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of advanced corticosteroid-based medications.
• Controlled-Release Formulations: Development of depot injections, implants, or microsphere systems for sustained delivery of methylprednisolone.
• Anti-inflammatory & Immunosuppressive Therapies: Prodrug for targeted treatment of severe inflammatory conditions, autoimmune disorders, and allergic reactions.
• Research & Development: Used in preclinical and clinical studies to investigate novel drug delivery mechanisms and pharmacokinetics.
• Veterinary Medicine: Potential application in developing long-acting anti-inflammatory treatments for animals.
• Specialty Chemical Synthesis: Building block for creating more complex steroid derivatives with modified release profiles.

Basic Information

Product Name	Methylprednisolonesuleptanate
CAS No.	60239-66-9
Molecular Formula	C29H40O7
Molecular Weight	500.63 g/mol
Synonyms	Methylprednisolone Suleptanate; Methylprednisolone 21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione; 21-(3-Carboxypropionyloxy)-6α-methylprednisolone; 6α-Methylprednisolone 21-hemisuccinate; U-67590A; Methylprednisolone Hemisuccinate (common name for the ester); Depo-Medrol related ester (trade name reference)
EINECS	Contact for details

Quality Control

Our Methylprednisolonesuleptanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) documenting identity, purity, and related substances are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.