Description

n-[4-[2-Hydroxy-3-[(1-Methylethyl)Amino]Propoxy]Phenyl]Acetamide Monohydrochloride is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) salt form. This compound is critical for ensuring the stability, bioavailability, and efficacy of final drug formulations. It is primarily required by pharmaceutical R&D laboratories and manufacturing facilities engaged in the synthesis of specialized cardiovascular and β-blocker medications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced β-adrenergic blocking agents (β-blockers).
• Active Pharmaceutical Ingredient (API): Used as the active salt form in the final formulation of specific prescription drugs.
• Cardiovascular Drug Research: Essential for R&D focused on hypertension, angina pectoris, and arrhythmia treatments.
• Process Development & Scale-up: Serves as a reference standard and starting material for process optimization from lab to commercial scale.
• Analytical Standard: Used in quality control laboratories as a high-purity reference standard for HPLC, LC-MS, and NMR analysis.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research for related drug compounds.

Basic Information

Product Name	n-[4-[2-Hydroxy-3-[(1-Methylethyl)Amino]Propoxy]Phenyl]Acetamide Monohydrochloride
CAS No.	6996-43-6
Molecular Formula	C14H23ClN2O3
Molecular Weight	302.80 g/mol
Synonyms	Acetamide, N-[4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-, monohydrochloride; 4'-[2-Hydroxy-3-(isopropylamino)propoxy]acetanilide Hydrochloride; Acebutolol Related Compound B (Hydrochloride Salt); Acebutolol Impurity B HCl; 1-(4-Acetamidophenoxy)-3-(isopropylamino)-2-propanol Hydrochloride; (±)-Acebutolol Hydrochloride; Sectral Impurity B; RS-Acebutolol Hydrochloride
EINECS	Contact for details

Quality Control

Our n-[4-[2-Hydroxy-3-[(1-Methylethyl)Amino]Propoxy]Phenyl]Acetamide Monohydrochloride is manufactured under strict quality management systems. We provide material that meets exacting standards for pharmaceutical development, supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch. Our quality commitment aligns with ICH guidelines and current Good Manufacturing Practice (cGMP) principles for APIs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Unknown Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.