Description

11Beta,17,21-Trihydroxypregn-4-Ene-3,20-Dione 21-Heptanoate is a high-purity steroid derivative, specifically a heptanoate ester of hydrocortisone. This compound is valued for its role as a key pharmaceutical intermediate in the synthesis of advanced corticosteroid APIs. It is primarily required by research institutions and manufacturers in the pharmaceutical and life sciences sectors for the development and production of specialized anti-inflammatory and immunosuppressive medications.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of potent topical and systemic corticosteroid active pharmaceutical ingredients (APIs).
• Steroid Prodrug Development: Used in research to create prodrug forms with modified pharmacokinetic profiles, such as enhanced lipophilicity and prolonged release.
• Biochemical Research: Serves as a reference standard and reagent in metabolic pathway studies and steroid hormone receptor research.
• Veterinary Medicine: Employed in the formulation of long-acting anti-inflammatory treatments for animals.
• Advanced Material Synthesis: Investigated for potential use in creating specialized polymer coatings or delivery systems in material science.

Basic Information

Product Name	11Beta,17,21-Trihydroxypregn-4-Ene-3,20-Dione 21-Heptanoate
CAS No.	6678-15-5
Molecular Formula	C28H42O6
Molecular Weight	474.63 g/mol
Synonyms	Hydrocortisone 21-Heptanoate; Cortisol 21-Heptanoate; 11β,17,21-Trihydroxypregn-4-ene-3,20-dione 21-heptanoate; 21-Heptanoyloxy-11β,17α-dihydroxypregn-4-ene-3,20-dione; Hydrocortisone Enanthate; NSC 113935
EINECS	Contact for details

Quality Control

Our 11Beta,17,21-Trihydroxypregn-4-Ene-3,20-Dione 21-Heptanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets stringent specifications for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.