Description

Prednisone 17, 21-Diacetate is a key pharmaceutical intermediate and a diacetylated derivative of the corticosteroid prednisone. This compound is valued for its role in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs) and for research into anti-inflammatory and immunosuppressive agents. It is primarily utilized by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of corticosteroid APIs and other steroid derivatives.
• Research & Development: Used in biochemical and pharmacological research to study steroid metabolism, structure-activity relationships, and mechanism of action.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
• Process Chemistry: Employed in process development and scale-up for the manufacture of steroid-based drugs.

Basic Information

Product Name	Prednisone 17, 21-Diacetate
CAS No.	6677-19-6
Molecular Formula	C25H30O7
Molecular Weight	442.50 g/mol
Synonyms	17α,21-Dihydroxypregna-1,4-diene-3,11,20-trione 17,21-diacetate; Prednisone Diacetate; 1,4-Pregnadiene-17α,21-diol-3,11,20-trione 17,21-Diacetate; NSC 527986; 17α,21-Diacetoxypregna-1,4-diene-3,11,20-trione; Prednisone 17-Acetate 21-Acetate
EINECS	229-718-9

Quality Control

Our Prednisone 17, 21-Diacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.