Description

Triprolidine Hydrochloride is a potent, selective histamine H1-receptor antagonist widely recognized for its efficacy in managing allergic conditions. This active pharmaceutical ingredient (API) is valued for its reliable performance in pharmaceutical formulations, ensuring consistent therapeutic outcomes. It is primarily required by manufacturers in the pharmaceutical industry for the production of antihistamine medications, as well as by research institutions for pharmacological studies.

Application

• Pharmaceutical API: Primary active ingredient in prescription and over-the-counter (OTC) antihistamine tablets, syrups, and capsules for allergy relief.
• Combination Cold & Flu Medications: Used in multi-symptom relief formulations alongside decongestants and analgesics.
• Veterinary Pharmaceuticals: Incorporated into medications for treating allergic reactions in animals.
• Clinical Research: Serves as a reference standard and key compound in studies of histamine receptor function and allergy mechanisms.
• Formulation Development: Utilized in R&D for developing new drug delivery systems, such as sustained-release or fast-dissolving formulations.

Basic Information

Product Name	Triprolidine Hydrochloride
CAS No.	6138-79-0
Molecular Formula	C19H22N2 • HCl
Molecular Weight	314.85 g/mol
Synonyms	(E)-2-[3-(1-Pyrrolidinyl)-1-p-tolylprop-1-enyl]pyridine hydrochloride; Triprolidine HCl; Triprolidinium Chloride; Actidil; Actifed; Pro-Actidil; Baynas; 1-Pyrrolidinepropanol, β-(2-pyridyl)-p-methylstyryl-, hydrochloride; (E)-Triprolidine Hydrochloride
EINECS	228-118-8

Quality Control

Our Triprolidine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.