Description

5-Dihydroaldosterone is a key intermediate and reference standard in the synthesis and analytical research of steroid hormones. This compound matters for its critical role in the study of mineralocorticoid pathways and related metabolic processes. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for developing and calibrating assays, as well as for use in advanced synthetic routes for steroid-based active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods like HPLC and LC-MS for quantifying aldosterone and related metabolites in biological samples.
• Biochemical Research: Serves as a crucial intermediate in studying the biosynthesis, metabolism, and receptor binding of mineralocorticoid hormones.
• API Synthesis: Acts as a sophisticated building block in the multi-step synthesis of novel steroid-based therapeutic agents.
• Diagnostic Kit Development: Employed in the production and validation of immunoassay kits for endocrine disorder diagnostics.
• Metabolite Studies: Essential for in-vitro and in-vivo research into the metabolic pathways of aldosterone.

Basic Information

Product Name	5-Dihydroaldosterone
CAS No.	6005-92-1
Molecular Formula	C21H30O4
Molecular Weight	346.46 g/mol
Synonyms	5α-Dihydroaldosterone; 5β-Dihydroaldosterone; 18,11-Hemiacetal of 5α-Dihydroaldosterone; 11β,21-Dihydroxy-3,20-dioxo-5α-pregnan-18-al; Aldosterone Dihydro Derivative; 5-DHA; 5α-DHA
EINECS	Contact for details

Quality Control

Every batch of our 5-Dihydroaldosterone is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements for research and reference materials. A detailed Certificate of Analysis (COA) specifying purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.