Description

Butanedioic Acid, 2-Fluoro-3-Hydroxy- is a fluorinated derivative of succinic acid, serving as a versatile chiral building block in advanced organic synthesis. Its unique structure, featuring both fluorine and hydroxyl functional groups, makes it a critical intermediate for creating complex molecules with tailored biological and physical properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of fluorinated drug candidates, including protease inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Biochemical Research: Employed as a probe or substrate in enzymatic studies to investigate fluorination effects on biochemical pathways.
• Material Science: A potential monomer or modifier for synthesizing specialty polymers with unique surface properties or degradation profiles.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring fluorinated, multifunctional intermediates.

Basic Information

Product Name	Butanedioic Acid, 2-Fluoro-3-Hydroxy-
CAS No.	685-65-4
Molecular Formula	C4H5FO4
Molecular Weight	136.08 g/mol
Synonyms	2-Fluoro-3-hydroxysuccinic acid; 3-Hydroxy-2-fluorobutanedioic acid; 2-Fluoro-3-hydroxybutanedioic acid; (2R,3S)-2-Fluoro-3-hydroxysuccinic acid (for enantiopure form); Fluorohydroxysuccinic acid; Hydroxyfluorosuccinic acid; Succinic acid, 2-fluoro-3-hydroxy-
EINECS	Contact for details

Quality Control

Our Butanedioic Acid, 2-Fluoro-3-Hydroxy- is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.