Description

3-Chloro-4-Fluorobenzyl Cyanide is a versatile and high-purity fluorinated aromatic intermediate essential for advanced organic synthesis. Its unique molecular structure, featuring both chloro and fluoro substituents, makes it a critical building block for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in high-performance displays (LCDs).
• Organic Electronics: Intermediate in the production of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized fluorinated dyes and pigments with improved lightfastness and color properties.
• Chemical Research & Development: A valuable reagent for constructing complex benzyl-nitrile scaffolds in medicinal chemistry and material science research.

Basic Information

Product Name	3-Chloro-4-Fluorobenzyl Cyanide
CAS No.	658-98-0
Molecular Formula	C8H5ClFN
Molecular Weight	169.58 g/mol
Synonyms	(3-Chloro-4-fluorophenyl)acetonitrile; 2-(3-Chloro-4-fluorophenyl)acetonitrile; 3-Chloro-4-fluorobenzeneacetonitrile; 3-Chloro-4-fluorophenylacetonitrile; α-Cyano-3-chloro-4-fluorotoluene; 3-Chloro-4-fluoro-benzylcyanide; 3-Chloro-4-fluoro-α-tolunitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-4-Fluorobenzyl Cyanide is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade typically meets a purity specification of ≥98% (by HPLC), with stringent controls on key impurities. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.