Description

2-Hydroxy-4-Pregnene-3,20-Dione is a high-purity steroid intermediate of significant importance in pharmaceutical synthesis. This compound serves as a critical building block for the development of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in steroid hormone research and production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various steroid hormones and related therapeutic agents.
• Research & Development: Used in biochemical and pharmacological research to study steroid metabolism and receptor interactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• API Synthesis: Employed in multi-step synthetic routes for the production of complex steroid-based active pharmaceutical ingredients.

Basic Information

Product Name	2-Hydroxy-4-Pregnene-3,20-Dione
CAS No.	604-28-4
Molecular Formula	C21H30O3
Molecular Weight	330.46 g/mol
Synonyms	2α-Hydroxyprogesterone; 2α-Hydroxy-4-pregnene-3,20-dione; 2-Hydroxyprogesterone; 2α-Hydroxypregn-4-ene-3,20-dione; Pregn-4-ene-2α-ol-3,20-dione; 2α-Hydroxy-δ4-pregnene-3,20-dione
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-4-Pregnene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is kept tightly sealed in a dry environment away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.