Description

1,4-Pregnadien-17,20-Beta, 21-Triol-3,11-Dione is a high-purity steroid derivative and a key synthetic intermediate in pharmaceutical manufacturing. This compound is critical for the research and development of advanced corticosteroid and anti-inflammatory drug candidates. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in steroid chemistry and novel therapeutic synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of potent glucocorticoids and other steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and structural modification of new steroid-based therapeutics with targeted biological activity.
• Reference Standard: Serves as an analytical standard in quality control laboratories for method development and impurity profiling of related steroid products.
• Biochemical Research: Employed in studies investigating steroid hormone pathways, receptor binding, and metabolic processes.

Basic Information

Product Name	1,4-Pregnadien-17,20-Beta, 21-Triol-3,11-Dione
CAS No.	600-92-0
Molecular Formula	C21H28O5
Molecular Weight	360.45 g/mol
Synonyms	Prednisolone 21-Acetate Impurity A; 11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione; 1,4-Pregnadiene-11β,17α,21-triol-3,20-dione; 17α,21-Dihydroxypregna-1,4-diene-3,11,20-trione; Prednisolone Related Compound A; 11-Deoxy-21-hydroxycortisone; NSC 10483; 11-Deoxy-21-hydroxyprednisone
EINECS	Contact for details

Quality Control

Our 1,4-Pregnadien-17,20-Beta, 21-Triol-3,11-Dione is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.