Description

Allotetrahydrocorticosterone CAS NO 600-63-5 is a synthetic steroid derivative, specifically a reduced metabolite of corticosterone. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a reference standard and a key intermediate in the study of steroid hormone metabolism and synthesis. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in advanced steroid chemistry, endocrinology research, and the development of analytical methods.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for the quantification and identification of steroid metabolites in research and quality control laboratories.
• Biochemical Research: Serves as a critical intermediate or substrate in studies investigating corticosteroid biosynthesis, metabolic pathways, and enzyme kinetics.
• Endocrinology Studies: Employed in in-vitro and in-vivo research models to explore the physiological effects and regulatory mechanisms of reduced corticosterone derivatives.
• Fine Chemical Synthesis: Acts as a key building block for the custom synthesis of more complex steroid analogs and novel chemical entities for therapeutic screening.
• Analytical Method Development: Essential for developing and validating sensitive analytical techniques such as HPLC, LC-MS, and GC-MS for steroid profiling.

Basic Information

Product Name	Allotetrahydrocorticosterone
CAS No.	600-63-5
Molecular Formula	C21H34O4
Molecular Weight	350.49 g/mol
Synonyms	5α-Tetrahydrocorticosterone; 3α,11β,21-Trihydroxy-5α-pregnan-20-one; 5α-Pregnane-3α,11β,21-triol-20-one; 11β,21-Dihydroxy-5α-pregnane-3,20-dione; Allo-Tetrahydrocorticosterone; 5α-THC; 5α-THB; ATHB
EINECS	Contact for details

Quality Control

Our Allotetrahydrocorticosterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing specific results for identity, assay, and purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.