Description

5-β-Dihydrocortisone is a synthetic corticosteroid derivative and a key intermediate in the production of various steroidal pharmaceuticals. This compound is valued for its role in the synthesis of more complex anti-inflammatory and immunosuppressive agents, offering a critical building block for advanced pharmaceutical manufacturing. It is primarily required by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the development and production of steroid-based therapeutics.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potent corticosteroid drugs.
• Biochemical Research: Used in metabolic studies and research on steroid hormone pathways and receptor interactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Fine Chemical Synthesis: Employed in custom synthesis and the development of novel steroidal compounds with potential therapeutic applications.

Basic Information

Product Name	5-β-Dihydrocortisone
CAS No.	68-54-2
Molecular Formula	C21H28O5
Molecular Weight	360.45 g/mol
Synonyms	5β-Dihydrocortisone; 17,21-Dihydroxypregnane-3,11,20-trione; 5β-Pregnane-3,11,20-trione-17,21-diol; 11-Dehydrocorticosterone; NSC 11319; 5β-Dihydro-11-dehydrocorticosterone; 17α,21-Dihydroxy-5β-pregnane-3,11,20-trione
EINECS	200-694-1

Quality Control

Our 5-β-Dihydrocortisone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets high-grade specifications suitable for pharmaceutical research and synthesis. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.