Description

Fluocinolone Acetonide is a potent synthetic glucocorticoid corticosteroid widely recognized for its anti-inflammatory and antipruritic properties. Its high potency and efficacy make it a critical active pharmaceutical ingredient (API) for treating severe dermatological conditions. This compound is essential for manufacturers in the pharmaceutical and dermatological sectors developing topical creams, ointments, and solutions.

Application

• Primary Active Pharmaceutical Ingredient (API) in topical corticosteroid formulations for psoriasis, eczema, and atopic dermatitis.
• Key component in prescription-strength creams and ointments for severe inflammatory skin disorders.
• Used in the formulation of scalp solutions and gels for treating scalp psoriasis and seborrheic dermatitis.
• Incorporated into otic (ear) solutions for managing inflammatory ear canal conditions.
• Essential raw material for compounding pharmacies creating specialized dermatological treatments.
• Used in veterinary medicine for topical anti-inflammatory applications.
• Reference standard in analytical laboratories for quality control and pharmaceutical research.

Basic Information

Product Name	Fluocinolone Acetonide
CAS No.	67-73-2
Molecular Formula	C24H30F2O6
Molecular Weight	452.49 g/mol
Synonyms	6α,9α-Difluoro-16α-hydroxyprednisolone 16,17-acetonide; Fluocinonide Related Compound A; 6α-Fluoro-16α-hydroxytriamcinolone acetonide; Fluocinolone Acetonide USP; Synalar; Synandone; Fluocinonide Impurity A; Fluocinolonacetonide
EINECS	200-668-5

Quality Control

Our Fluocinolone Acetonide is manufactured under strict quality systems to meet or exceed pharmacopeial standards. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC, to ensure compliance with USP, EP, and CP monographs. A detailed Certificate of Analysis (COA) documenting purity, related substances, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.