Description

Cyclooctanol, 4-Fluoro-, (1R,4S)-Rel- (9Ci) is a chiral fluorinated cyclooctanol derivative, a high-value specialty chemical building block. Its defined stereochemistry and fluorine substitution make it a critical intermediate for synthesizing complex molecules with targeted biological activity. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where precise molecular architecture is required for efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom and specific stereochemistry can enhance metabolic stability and target binding.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or modifier for creating specialty polymers with unique thermal or chemical resistance properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and biological pathways due to its fluorine label and rigid structure.

Basic Information

Product Name	Cyclooctanol, 4-Fluoro-, (1R,4S)-Rel- (9Ci)
CAS No.	596826-84-5
Molecular Formula	C8H15FO
Molecular Weight	146.20 g/mol
Synonyms	(1R,4S)-rel-4-Fluorocyclooctanol; rel-(1R,4S)-4-Fluorocyclooctanol; 4-Fluorocyclooctanol (rel-(1R,4S)-form); Fluorocyclooctanol; Cyclooctanol, 4-fluoro-, (1R,4S)-rel-; (1R,4S)-4-Fluorocyclooctan-1-ol (relative configuration); Chiral Fluorinated Cyclooctanol
EINECS	Contact for details

Quality Control

Our production of Cyclooctanol, 4-Fluoro-, (1R,4S)-Rel- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (rel-(1R,4S))
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.