Description

Bicyclo[1.1.1]Pentan-1-Ol, 3-(Trifluoromethyl)- (9Ci) is a highly specialized and synthetically valuable fluorinated bicyclic alcohol. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for the development of novel bioactive molecules. It is primarily sought after by R&D and process chemistry teams in the pharmaceutical, agrochemical, and advanced materials sectors for its unique structural and electronic properties conferred by the bicyclo[1.1.1]pentane and trifluoromethyl motifs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the bicyclic scaffold can enhance metabolic stability and bioavailability.
• Medicinal Chemistry: Employed as a spatial disconnection or bioisostere in drug discovery programs to improve the potency, selectivity, and pharmacokinetic profiles of lead compounds.
• Material Science Research: Acts as a monomer or functional additive in the development of specialty polymers and advanced materials with tailored surface properties.
• Organic Synthesis Reagent: Serves as a versatile synthon for constructing complex, three-dimensional molecular architectures in academic and industrial research.

Basic Information

Product Name	Bicyclo[1.1.1]Pentan-1-Ol, 3-(Trifluoromethyl)- (9Ci)
CAS No.	585532-19-0
Molecular Formula	C6H7F3O
Molecular Weight	152.11 g/mol
Synonyms	3-(Trifluoromethyl)bicyclo[1.1.1]pentan-1-ol; 3-(Trifluoromethyl)-1-bicyclo[1.1.1]pentanol; 1-Bicyclo[1.1.1]pentanol, 3-(trifluoromethyl)-; Bicyclo[1.1.1]pentan-1-ol, 3-(trifluoromethyl)-; 3-Trifluoromethylbicyclo[1.1.1]pentan-1-ol; 585532-19-0; 3-(Trifluoromethyl)-1-hydroxybicyclo[1.1.1]pentane
EINECS	Contact for details

Quality Control

Our production of Bicyclo[1.1.1]Pentan-1-Ol, 3-(Trifluoromethyl)- adheres to stringent quality protocols suitable for high-value chemical intermediates. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results from NMR, HPLC, and GC-MS are provided to guarantee the material meets your specific R&D or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.