Description

2-Propynenitrile,3-(3,5-Difluorophenyl)-(9Ci) is a specialized fluorinated nitrile building block with the CAS registry number 575433-44-2. This compound is valued for its unique molecular structure, which incorporates both a reactive cyanoalkyne group and a difluorophenyl moiety, making it a versatile intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules, particularly in the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides where the difluorophenyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced functional materials with tailored properties.
• Ligand Synthesis: Employed in organometallic chemistry for creating novel ligands used in catalysis and asymmetric synthesis.
• Fluorine Chemistry Studies: A valuable reagent for academic and industrial research exploring the effects of fluorine substitution on reactivity and molecular interactions.
• Fine Chemical Synthesis: Intermediate for producing complex fluorinated fine chemicals and dyes.

Basic Information

Product Name	2-Propynenitrile,3-(3,5-Difluorophenyl)-(9Ci)
CAS No.	575433-44-2
Molecular Formula	C9H3F2N
Molecular Weight	163.13 g/mol
Synonyms	3-(3,5-Difluorophenyl)-2-propynenitrile; 3,5-Difluorophenylpropiolonitrile; 3-(3,5-Difluorophenyl)propiolonitrile; 2-Propynenitrile, 3-(3,5-difluorophenyl)-; 575433-44-2; 3-(3,5-Difluorophenyl)prop-2-ynenitrile
EINECS	Contact for details

Quality Control

Our production of 2-Propynenitrile,3-(3,5-Difluorophenyl)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.