Description

Benzonitrile, 4-Chloro-3,5-Bis(Trifluoromethyl)- is a highly functionalized aromatic nitrile derivative, distinguished by its chloro and trifluoromethyl substituents. This compound serves as a versatile and valuable building block in advanced organic synthesis, particularly for introducing electron-deficient aromatic systems. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring trifluoromethylated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Building block for developing modern herbicides, fungicides, and insecticides where the chloro and trifluoromethyl groups contribute to biological activity and environmental persistence.
• Ligand and Catalyst Development: Used to prepare specialized ligands for transition metal catalysis, leveraging the nitrile and halogen functionalities for coordination chemistry.
• Material Science Research: Monomer or precursor for synthesizing advanced polymers, liquid crystals, or organic electronic materials with specific optoelectronic properties.
• Fluorine Chemistry Studies: A valuable substrate for investigating novel fluorination reactions and the unique properties imparted by multiple trifluoromethyl groups.

Basic Information

Product Name	Benzonitrile, 4-Chloro-3,5-Bis(Trifluoromethyl)-
CAS No.	573768-09-9
Molecular Formula	C9H2ClF6N
Molecular Weight	273.56 g/mol
Synonyms	4-Chloro-3,5-bis(trifluoromethyl)benzonitrile; 3,5-Bis(trifluoromethyl)-4-chlorobenzonitrile; 4-Chloro-α,α,α,α',α',α'-hexafluoro-3,5-xylyl cyanide; 2-Chloro-α,α,α,α',α',α'-hexafluoro-3,5-dimethylbenzonitrile; 4-Chloro-3,5-di(trifluoromethyl)benzonitrile; PCBTF (context-specific abbreviation); 4-Chloro-3,5-bis(trifluoromethyl)phenyl cyanide
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-Chloro-3,5-Bis(Trifluoromethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high-purity synthetic intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residue on Ignition	<0.1%
Related Substances (HPLC)	Total impurities <3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.