Description

Benzonitrile, 4-Amino-3-Methyl-2-(Trifluoromethyl)- (9Ci) is a specialized aromatic nitrile derivative featuring amino and trifluoromethyl substituents. This compound is a high-value pharmaceutical intermediate and agrochemical building block, prized for its unique molecular architecture that imparts desirable biological activity and metabolic stability. It is primarily utilized by R&D chemists and process development scientists in the life sciences and crop protection industries for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, antiviral, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Serves as a crucial building block for novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced efficacy and environmental profile.
• Material Science Research: Used in the synthesis of advanced organic materials, including liquid crystals and polymers with specific electronic or optical properties.
• Chemical Biology Probes: Employed in medicinal chemistry for creating labeled compounds and probes to study biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Benzonitrile, 4-Amino-3-Methyl-2-(Trifluoromethyl)- (9Ci)
CAS No.	573764-86-0
Molecular Formula	C9H7F3N2
Molecular Weight	200.16 g/mol
Synonyms	4-Amino-3-methyl-2-(trifluoromethyl)benzonitrile; 2-Trifluoromethyl-4-amino-3-methylbenzonitrile; 3-Methyl-4-amino-2-trifluoromethylbenzonitrile; 4-Amino-α,α,α-trifluoro-3-methyl-o-tolunitrile; 2-Cyano-6-methyl-5-(trifluoromethyl)aniline; 5-Amino-6-cyano-α,α,α-trifluoro-m-xylene
EINECS	Contact for details

Quality Control

Our production of Benzonitrile, 4-Amino-3-Methyl-2-(Trifluoromethyl)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthesis. Each lot is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all specifications. Our quality management system is designed to support cGMP compliance for advanced intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.