Description

Benzonitrile, 2-Ethoxy-4-(Trifluoromethyl)- (9Ci) CAS NO 548785-17-7 is a specialized organic compound featuring a benzonitrile core substituted with ethoxy and trifluoromethyl groups. This unique molecular architecture makes it a valuable high-purity building block for advanced chemical synthesis. It is primarily sought after by pharmaceutical and agrochemical research organizations for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Used in the synthesis of advanced electronic materials for displays and lighting, where its rigid, polar structure contributes to desired electro-optical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and cyano-group transformations to construct complex heterocyclic and aromatic systems.
• Fluorinated Compound Research: Acts as a standard or starting material in academic and industrial R&D focused on introducing fluorine atoms into organic molecules to modulate their physicochemical properties.

Basic Information

Product Name	Benzonitrile, 2-Ethoxy-4-(Trifluoromethyl)- (9Ci)
CAS No.	548785-17-7
Molecular Formula	C10H8F3NO
Molecular Weight	215.17 g/mol
Synonyms	2-Ethoxy-4-(trifluoromethyl)benzonitrile; 4-(Trifluoromethyl)-2-ethoxybenzonitrile; 2-Ethoxy-α,α,α-trifluoro-p-tolunitrile; 2-Ethoxy-4-trifluoromethylbenzonitrile; p-Cyano-3-ethoxybenzotrifluoride; 3-Ethoxy-4-cyanobenzotrifluoride; Benzonitrile, 2-ethoxy-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of Benzonitrile, 2-Ethoxy-4-(Trifluoromethyl)- adheres to stringent GMP and ISO 9001 guidelines to ensure batch-to-batch consistency and traceability. Every lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.