Description

(2R)-1-[(1-Methylethyl)Amino]-3-[4-[(2-Propoxyethoxy)Methyl]Phenoxy]-2-Propanol CAS NO 539823-39-7 is a high-purity, chiral organic compound belonging to the class of aryloxypropanolamine derivatives. This compound is valued for its role as a key synthetic intermediate in the development of active pharmaceutical ingredients (APIs), particularly those targeting adrenergic receptors. It is essential for research and manufacturing organizations in the pharmaceutical and fine chemical sectors requiring precise stereochemistry and high chemical purity for advanced drug synthesis and process development.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of β-adrenergic receptor antagonists (β-blockers) and related therapeutic agents.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new cardiovascular and neurological drugs.
• Process Chemistry: Serves as a key starting material or intermediate in the scale-up and optimization of API manufacturing processes under GMP conditions.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, optically active molecules for various advanced chemical applications.

Basic Information

Product Name	(2R)-1-[(1-Methylethyl)Amino]-3-[4-[(2-Propoxyethoxy)Methyl]Phenoxy]-2-Propanol
CAS No.	539823-39-7
Molecular Formula	C19H33NO4
Molecular Weight	339.47 g/mol
Synonyms	(R)-1-Isopropylamino-3-[4-[(2-propoxyethoxy)methyl]phenoxy]-2-propanol; (2R)-1-(Isopropylamino)-3-[4-[(2-propoxyethoxy)methyl]phenoxy]propan-2-ol; 1-(Isopropylamino)-3-[4-[(2-propoxyethoxy)methyl]phenoxy]-2-propanol, (R)-; 539823-39-7; UNII-4Q6X2P8V8I; 4Q6X2P8V8I; AR-1H/006/AR-1H/006/AR-1H/006
EINECS	Contact for details

Quality Control

Our (2R)-1-[(1-Methylethyl)Amino]-3-[4-[(2-Propoxyethoxy)Methyl]Phenoxy]-2-Propanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.