Description

5-Fluoro-2-(Methylsulphonyl)Nitrobenzene is a high-purity, multi-functional aromatic building block of significant importance in advanced organic synthesis. Its unique molecular architecture, featuring electron-withdrawing nitro and methylsulfonyl groups adjacent to a fluorine atom, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and stability.
• Material Science Research: Serves as a building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and pigments.
• Cross-Coupling Reactions: The reactive nitro and halogen groups make it a suitable substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	5-Fluoro-2-(Methylsulphonyl)Nitrobenzene
CAS No.	518990-79-9
Molecular Formula	C7H6FNO4S
Molecular Weight	219.19 g/mol
Synonyms	1-Fluoro-2-(methylsulfonyl)-4-nitrobenzene; 2-Fluoro-5-nitro phenyl methyl sulfone; 5-Fluoro-2-(methylsulfonyl)nitrobenzene; 2-Methylsulfonyl-5-fluoronitrobenzene; 4-Nitro-2-(methylsulfonyl)fluorobenzene; 5-Fluoro-2-methylsulfonylnitrobenzene; Benzene, 1-fluoro-2-(methylsulfonyl)-4-nitro-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Methylsulphonyl)Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.