Description

3-Fluoro-4-Nitrophenylacetonitrile is a versatile fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its molecular structure, featuring both an electron-withdrawing nitro group and a reactive nitrile moiety, makes it a critical intermediate for constructing complex molecules with high precision. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating fluorinated aromatic cores in electronic display and lighting materials.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized, light-fast dyes and colorants.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Biology Probes: Utilized in the design of fluorinated probes and tags for studying biological processes.

Basic Information

Product Name	3-Fluoro-4-Nitrophenylacetonitrile
CAS No.	503315-75-1
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	2-(3-Fluoro-4-nitrophenyl)acetonitrile; (3-Fluoro-4-nitrophenyl)acetonitrile; 3-Fluoro-4-nitrobenzyl cyanide; 4-Nitro-3-fluorobenzyl cyanide; α-Cyano-3-fluoro-4-nitrotoluene; 2-(3-Fluoro-4-nitrophenyl)ethanenitrile; 503315-75-1; 3-Fluoro-4-nitrobenzeneacetonitrile
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Nitrophenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.