Description

2-(Benzyloxy)-4-Fluorobenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a benzyl-protected phenol ether and a fluorine substituent, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Advanced Polymer Chemistry: Employed in the creation of specialty polymers and resins with specific thermal, optical, or chemical resistance properties.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	2-(Benzyloxy)-4-Fluorobenzonitrile
CAS No.	503293-06-9
Molecular Formula	C₁₄H₁₀FNO
Molecular Weight	227.24 g/mol
Synonyms	4-Fluoro-2-(phenylmethoxy)benzonitrile; Benzonitrile, 2-(benzyloxy)-4-fluoro-; 2-Benzyloxy-4-fluorobenzonitrile; 4-Fluoro-2-benzyloxybenzonitrile; 2-(Benzyloxy)-4-fluorobenzene carbonitrile; 503293-06-9; 2-(Phenylmethoxy)-4-fluorobenzonitrile
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)-4-Fluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of R&D and cGMP-grade production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.