Description

3-Fluoro[1,1'-Biphenyl]-4-Carbonitrile is a high-purity fluorinated biphenyl derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which combines a fluorine substituent and a nitrile group on a biphenyl scaffold, enabling precise modifications in complex chemical architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and anti-inflammatory drug candidates.
• Agrochemical Research: Used in the synthesis of novel herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals and electron-transport materials for display and lighting technologies.
• Organic Electronics: Employed in the construction of conjugated polymers and small molecules for organic field-effect transistors (OFETs) and photovoltaic cells.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent probes and molecular tags due to the biphenyl core's rigidity and modifiability.

Basic Information

Product Name	3-Fluoro[1,1'-Biphenyl]-4-Carbonitrile
CAS No.	503177-15-9
Molecular Formula	C₁₃H₈FN
Molecular Weight	197.21 g/mol
Synonyms	3-Fluoro-4-cyanobiphenyl; 4'-Fluoro-[1,1'-biphenyl]-4-carbonitrile; 3-Fluorobiphenyl-4-carbonitrile; [1,1'-Biphenyl]-4-carbonitrile, 3-fluoro-; 3-Fluoro-4'-cyanobiphenyl; 4-Cyano-3-fluorobiphenyl
EINECS	Contact for details

Quality Control

Our 3-Fluoro[1,1'-Biphenyl]-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.