Description

1,5-Dichloro-2-Fluoro-3-Nitrobenzene is a high-purity, multi-functional halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its precise substitution pattern makes it an indispensable intermediate for creating complex molecules with targeted properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogen and nitro functional groups.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex organic dyes and colorants.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Organic Synthesis Building Block: Utilized in nucleophilic aromatic substitution (SNAr) reactions to introduce amines, alkoxides, or other nucleophiles.

Basic Information

Product Name	1,5-Dichloro-2-Fluoro-3-Nitrobenzene
CAS No.	501644-37-7
Molecular Formula	C6H2Cl2FNO2
Molecular Weight	209.99 g/mol
Synonyms	2-Fluoro-3,5-dichloronitrobenzene; 3,5-Dichloro-2-fluoronitrobenzene; 1,3-Dichloro-4-fluoro-2-nitrobenzene; Benzene, 1,5-dichloro-2-fluoro-3-nitro-; 3-Nitro-2,4-dichlorofluorobenzene; 2,4-Dichloro-3-nitrofluorobenzene; 501644-37-7 (CAS)
EINECS	Contact for details

Quality Control

Our 1,5-Dichloro-2-Fluoro-3-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.