Description

3'-(Trifluoromethyl)[1,1'-Biphenyl]-2-Carbonitrile is a high-value biphenyl derivative featuring a trifluoromethyl group and a nitrile functional group, making it a versatile and critical building block in advanced organic synthesis. Its unique structure offers excellent chemical stability and reactivity, which is essential for creating complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the development of electronic materials for displays and lighting due to its rigid biphenyl core and electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and cyano-group transformations to construct complex aromatic systems.
• Chemical Research & Development: Utilized in academic and industrial R&D settings for method development and exploring new reaction pathways in fluorine chemistry.
• Material Science: Investigated as a monomer or additive for specialty polymers and coatings to impart specific thermal or chemical resistance properties.

Basic Information

Product Name	3'-(Trifluoromethyl)[1,1'-Biphenyl]-2-Carbonitrile
CAS No.	501427-87-8
Molecular Formula	C14H8F3N
Molecular Weight	247.22 g/mol
Synonyms	2-Cyano-3'-(trifluoromethyl)biphenyl; [1,1'-Biphenyl]-2-carbonitrile, 3'-(trifluoromethyl)-; 3'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carbonitrile; 2-(3-(Trifluoromethyl)phenyl)benzonitrile; 3-Trifluoromethyl-2-cyanobiphenyl
EINECS	Contact for details

Quality Control

Our production of 3'-(Trifluoromethyl)[1,1'-Biphenyl]-2-Carbonitrile adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality system is designed to meet the rigorous standards required for pharmaceutical and agrochemical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.