Description

2-Methoxy-6-Fluorobenzyl Cyanide is a versatile fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both methoxy and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic cores in electronic materials, contributing to improved charge transport, thermal stability, and optical properties.
• Advanced Polymer Chemistry: Employed in the creation of specialty polymers and high-performance resins with enhanced chemical resistance and specific dielectric characteristics.
• Chemical Research & Development: A valuable reagent for method development and exploring new reaction pathways in fluoroorganic chemistry and palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	2-Methoxy-6-Fluorobenzyl Cyanide
CAS No.	500912-18-5
Molecular Formula	C9H8FNO
Molecular Weight	165.16 g/mol
Synonyms	2-Fluoro-6-methoxybenzyl cyanide; (2-Fluoro-6-methoxyphenyl)acetonitrile; 6-Fluoro-2-methoxybenzyl cyanide; 2-Methoxy-6-fluorobenzeneacetonitrile; α-Cyano-2-fluoro-6-methoxytoluene; 2-Fluoro-6-methoxybenzyl nitrile; (6-Fluoro-2-methoxyphenyl)acetonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Methoxy-6-Fluorobenzyl Cyanide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.