Description

(S)-Bunitrolol CAS NO 59995-59-4 is a high-purity enantiomerically pure form of the β-adrenergic receptor antagonist (β-blocker) bunitrolol. This compound is of significant value in pharmaceutical research and development, particularly for studying stereoselective drug action and metabolism. It serves as a critical chiral intermediate and reference standard for analytical method development and pharmacological studies. Organizations in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors require this material for precision research and high-value product development.

Application

• As a chiral building block in the research and synthesis of novel β-blocker pharmaceuticals.
• As a pharmacological reference standard for in-vitro and in-vivo studies targeting β-adrenergic receptors.
• For use in analytical method development and validation, including HPLC and chiral separation techniques.
• In metabolism and pharmacokinetics (DMPK) studies to understand the stereoselective fate of drug molecules.
• As a key intermediate in the process development and scale-up of enantiomerically pure active pharmaceutical ingredients (APIs).
• For academic and institutional research exploring cardiovascular drug mechanisms and structure-activity relationships (SAR).

Basic Information

Product Name	(S)-Bunitrolol
CAS No.	59995-59-4
Molecular Formula	C17H20N2O3
Molecular Weight	300.35 g/mol
Synonyms	(S)-(-)-Bunitrolol; (S)-Bunitrolol; Levobunitrolol; (S)-1-(2-Cyano-4-hydroxyphenoxy)-3-[(1,1-dimethylethyl)amino]-2-propanol; Bunitrolol S-(-)-enantiomer; Bunitrolol (S)-isomer; (S)-Kö 1366; (S)-1-(tert-Butylamino)-3-(2-cyano-4-hydroxyphenoxy)-2-propanol
EINECS	Contact for details

Quality Control

Our (S)-Bunitrolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. We provide full traceability and Certificates of Analysis (COA) detailing identity, purity, and impurity profiles. Our quality commitment aligns with the expectations for pharmaceutical intermediates and reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.