Description

Pamatolol Sulfate CAS NO 59954-01-7 is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) belonging to the class of β-adrenergic blocking agents. It is critical for the research, development, and production of cardiovascular medications targeting hypertension and angina. This compound is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions engaged in advanced drug synthesis and formulation studies.

Application

• Pharmaceutical API Synthesis: Primary use as an active ingredient in the manufacture of β-blocker medications.
• Cardiovascular Drug Development: Key intermediate in R&D for new antihypertensive and anti-anginal therapies.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method validation in QC laboratories.
• Biochemical Research: Used in pharmacological studies to investigate β-adrenergic receptor mechanisms and interactions.
• Formulation Studies: Employed in the development of various dosage forms, including tablets and capsules.
• Generic Drug Manufacturing: A critical component in the production of generic versions of established β-blocker drugs.

Basic Information

Product Name	Pamatolol Sulfate
CAS No.	59954-01-7
Molecular Formula	C₁₇H₂₈N₂O₅S
Molecular Weight	372.48 g/mol
Synonyms	Pamatolol Sulphate; (±)-Pamatolol Sulfate; Pamatolol Hemisulfate; 1-(tert-Butylamino)-3-[(2-methylindol-4-yl)oxy]-2-propanol Sulfate; 4-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-2-methyl-1H-indole Sulfate (1:1); Pamatolol Sulfate Salt
EINECS	Contact for details

Quality Control

Our Pamatolol Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) documenting full compliance are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.