Description

(8S-Cis)-10-((3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyl)Oxy)-8 -((Benzoyloxy)Acetyl)-7,8,9,10-Tetrahydro-6,8,11-Trihydroxy-1-Methoxy- 5,12-Naphthacenedione is a complex, semi-synthetic anthracycline derivative with significant biological activity. This compound is valued for its role as a key intermediate in the synthesis of advanced pharmaceutical agents, particularly in oncology research. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in the development of novel chemotherapeutic drugs and biochemical probes.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of novel anthracycline-based chemotherapeutic agents and antibiotic drugs.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of action, structure-activity relationships (SAR), and drug resistance in cancer cells.
• Biochemical Probe: Serves as a tool compound in molecular biology for studying DNA intercalation, topoisomerase II inhibition, and cellular apoptosis pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for constructing complex molecular architectures with specific stereochemistry.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and method development for pharmaceutical manufacturing.
• Academic & Contract Research: Essential material for universities and CROs (Contract Research Organizations) conducting cutting-edge medicinal chemistry and drug discovery programs.

Basic Information

Product Name	(8S-Cis)-10-((3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyl)Oxy)-8 -((Benzoyloxy)Acetyl)-7,8,9,10-Tetrahydro-6,8,11-Trihydroxy-1-Methoxy- 5,12-Naphthacenedione
CAS No.	59367-03-2
Molecular Formula	C32H33NO12
Molecular Weight	623.61 g/mol
Synonyms	4'-O-Benzoyl-4'-deoxy-4'-epidaunorubicin; 4'-O-Benzoyl-4'-deoxy-4'-epidoxorubicin; 4'-O-Benzoyl-4'-deoxy-4'-epiadriamycin; 4'-O-Benzoyl-4'-deoxy-4'-epidau; Daunorubicin, 4'-O-benzoyl-4'-deoxy-4'-epi-; 4'-Epidaunorubicin 4'-benzoate; A derivative of 4'-epidoxorubicin; Benzoic acid, (8S-cis)-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione 8-ester
EINECS	Contact for details

Quality Control

Our (8S-Cis)-10-((3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyl)Oxy)-8 -((Benzoyloxy)Acetyl)-7,8,9,10-Tetrahydro-6,8,11-Trihydroxy-1-Methoxy- 5,12-Naphthacenedione is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, spectroscopic identification (IR, NMR), and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or under refrigeration (2-8°C) as specified. Due to its sensitivity to light and oxidation, long-term storage is recommended under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.