Description

14-((4-Methoxyphenyl)Diphenylmethoxy) Daunomycinone is a key synthetic intermediate and derivative of the anthracycline antibiotic daunorubicin. This compound matters for its critical role in pharmaceutical research and development, particularly in the synthesis of novel chemotherapeutic agents and the study of structure-activity relationships. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on oncology drug discovery and advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the research-scale synthesis of novel anthracycline-based anticancer agents and analogs.
• Biochemical Research: Used as a reference standard and probe in studies investigating DNA intercalation, topoisomerase II inhibition, and mechanisms of cytotoxicity.
• Structure-Activity Relationship (SAR) Studies: Essential for modifying the daunomycinone scaffold to explore and optimize biological activity, potency, and selectivity.
• Academic & Contract Research: Serves as a high-value starting material for synthetic organic chemistry projects in universities and CROs (Contract Research Organizations).
• Process Chemistry Development: Employed in the development and scale-up of synthetic routes for complex active pharmaceutical ingredients (APIs).
• Reference Material: Used for analytical method development, validation, and quality control of related pharmaceutical compounds.

Basic Information

Product Name	14-((4-Methoxyphenyl)Diphenylmethoxy) Daunomycinone
CAS No.	59326-04-4
Molecular Formula	C43H37NO8
Molecular Weight	695.76 g/mol
Synonyms	14-[(4-Methoxyphenyl)diphenylmethoxy]daunomycinone; 14-(4-Methoxyphenyl)diphenylmethoxy Daunomycinone; 14-O-[(4-Methoxyphenyl)diphenylmethyl]daunomycinone; Daunomycinone, 14-((4-methoxyphenyl)diphenylmethoxy)-; 14-(p-Methoxyphenyl)diphenylmethoxy Daunomycinone; 14-(4-Methoxyphenyl)diphenylmethoxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione; 14-(4-Methoxyphenyl)diphenylmethoxy-13-deoxydaunomycinone
EINECS	Contact for details

Quality Control

Our 14-((4-Methoxyphenyl)Diphenylmethoxy) Daunomycinone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.