Description

2-Bromo-3-Fluoronitrobenzene is a high-purity halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its unique combination of bromine, fluorine, and nitro functional groups on the aromatic ring makes it a versatile intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated and halogenated aromatic systems.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Intermediate for synthesizing complex, halogenated dyes and pigments with specific color fastness and properties.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination for carbon-carbon and carbon-heteroatom bond formation.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating compound libraries for screening in various R&D programs.

Basic Information

Product Name	2-Bromo-3-Fluoronitrobenzene
CAS No.	59255-94-6
Molecular Formula	C6H3BrFNO2
Molecular Weight	220.00 g/mol
Synonyms	1-Bromo-2-fluoro-3-nitrobenzene; 2-Fluoro-3-nitrobromobenzene; 3-Fluoro-2-nitrobromobenzene; Benzene, 1-bromo-2-fluoro-3-nitro-; 2-Bromo-3-fluoronitrobenzene; 2-Fluoro-6-nitrobromobenzene; o-Bromo-m-fluoronitrobenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluoronitrobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity while monitoring for specified impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	45 - 50 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.