Description

Pamatolol CAS NO 59110-35-9 is a high-purity pharmaceutical intermediate and research chemical belonging to the β-adrenergic blocking agent class. This compound is critical for the development and synthesis of advanced cardiovascular medications targeting hypertension and angina. It is primarily utilized by pharmaceutical R&D laboratories, API manufacturers, and academic research institutions focused on cardiology and medicinal chemistry.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: A key intermediate in the production of β-blocker drugs.
• Pharmaceutical Research & Development: Used in preclinical studies for investigating new cardiovascular therapies.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical labs.
• Process Chemistry: Employed in route scouting and scale-up optimization for efficient API manufacturing.
• Biochemical Studies: Utilized in pharmacological assays to study β-adrenergic receptor interactions and mechanisms.

Basic Information

Product Name	Pamatolol
CAS No.	59110-35-9
Molecular Formula	C15H24N2O3
Molecular Weight	280.36 g/mol
Synonyms	Pamatolol; Pamatolol Hydrochloride; 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[2-(2-propenyl)phenoxy]methyl]-, hydrochloride; (±)-Pamatolol; Pamatolol (base); UNII-1N8V8X66QJ; 1-(tert-Butylamino)-3-(o-allylphenoxy)-2-propanol
EINECS	Contact for details

Quality Control

Our Pamatolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Any single unknown impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.