Description

5-Fluoronaphthalene-1-Carbonitrile is a high-purity fluorinated naphthalene derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a nitrile group on the naphthalene core, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic systems to modulate bioavailability and metabolic stability.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and environmental persistence.
• Material Science: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic semiconductors with unique electronic and optical properties.
• Organic Synthesis & Catalysis: A valuable reagent in cross-coupling reactions and cyanation processes, enabling the construction of complex polycyclic aromatic structures for academic and industrial research.
• Fluorine Chemistry Studies: Used as a model compound in research focused on the effects of fluorine substitution on aromatic system reactivity and physical characteristics.

Basic Information

Product Name	5-Fluoronaphthalene-1-Carbonitrile
CAS No.	59080-27-2
Molecular Formula	C₁₁H₆FN
Molecular Weight	171.17 g/mol
Synonyms	1-Cyano-5-fluoronaphthalene; 5-Fluoro-1-naphthonitrile; 5-Fluoronaphthalene-1-carbonitrile; 1-Naphthalenecarbonitrile, 5-fluoro-; 5-Fluoro-1-cyanonaphthalene; 5-Fluoronaphthalen-1-carbonitril; 5-Fluoro-1-naphthalenecarbonitrile
EINECS	Contact for details

Quality Control

Our 5-Fluoronaphthalene-1-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.