Description

(7R-Cis)-9-Acetyl-7-((3-Amino-2,3,6-Trideoxy-β-L-Lyxo-Hexopyranosyl)Oxy)-7,8,9,10-Tetrahydro-6,9,11-Trihydroxy-5,12-Naphthacenedione is a complex, high-purity anthracycline derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and analytical characterization of novel therapeutic agents, particularly in oncology. It is essential for research institutions, pharmaceutical manufacturers, and fine chemical suppliers focused on developing next-generation cancer treatments and studying anthracycline pharmacology.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel anthracycline-based chemotherapeutic agents and analogs.
• Reference Standard: Used for quality control, method development, and validation in analytical laboratories (HPLC, LC-MS) to ensure the purity and identity of related drug substances.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR), mechanism of action, and metabolic pathways of anthracycline antibiotics.
• Antitumor Agent Development: Serves as a core scaffold for the research and development of new compounds targeting DNA topoisomerase II and other oncological targets.
• Academic & Contract Research: Utilized by universities and CROs (Contract Research Organizations) for preclinical studies and pharmacological evaluations.

Basic Information

Product Name	(7R-Cis)-9-Acetyl-7-((3-Amino-2,3,6-Trideoxy-β-L-Lyxo-Hexopyranosyl)Oxy)-7,8,9,10-Tetrahydro-6,9,11-Trihydroxy-5,12-Naphthacenedione
CAS No.	58976-06-0
Molecular Formula	C25H27NO10
Molecular Weight	501.48 g/mol
Synonyms	9-Acetyl-7-((3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione; (7R-cis)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione; 4-Demethoxy-7-O-(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)daunorubicinone; Aclacinomycin A Aglycone; 7-O-(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)aklavinone; Aclacinomycinone; Antibiotic MA 144 M1
EINECS	Contact for details

Quality Control

Our (7R-Cis)-9-Acetyl-7-((3-Amino-2,3,6-Trideoxy-β-L-Lyxo-Hexopyranosyl)Oxy)-7,8,9,10-Tetrahydro-6,9,11-Trihydroxy-5,12-Naphthacenedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and in original packaging until use to prevent degradation.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.